Gene expression profiling of NB4 cells following knockdown of nucleostemin using DNA microarrays

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Gene expression profiling of NB4 cells following knockdown of nucleostemin using DNA microarrays

Nucleostemin (NS) is mainly expressed in stem and tumor cells, and is necessary for the maintenance of their self-renewal and proliferation. Originally, NS was thought to exert its effects through inhibiting p53, while recent studies have revealed that NS is also able to function independently of p53. The present study performed a gene expression profiling analysis of p53‑mutant NB4 leukeima ce...

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ژورنال

عنوان ژورنال: Molecular Medicine Reports

سال: 2016

ISSN: 1791-2997,1791-3004

DOI: 10.3892/mmr.2016.5213